NIH to check Pfizer’s Paxlovid, different remedies as doable lengthy Covid treatments

Paxlovid, Pfizer’s anti-viral drugs to regard the coronavirus illness (COVID-19), is displayed on this image representation taken October 7, 2022.

Wolfgang Rattay | Reuters

The Nationwide Institutes of Well being mentioned Monday it introduced mid-stage scientific trials to check a minimum of 4 remedies, together with Pfizer’s antiviral Covid-19 tablet Paxlovid, as doable treatments for lengthy Covid. 

There is not any confirmed remedy for the situation, which refers to signs that proceed or broaden within the weeks or months following an preliminary Covid an infection. It impacts an estimated 23 million American citizens.

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Well being care suppliers most often attempt to deal with the regularly debilitating signs related to lengthy Covid, similar to persistent ache, reminiscence loss and intense fatigue. However the loss of a particular lengthy Covid remedy pushes some sufferers to hunt unproven – and doubtlessly unhealthy – therapies for the situation. 

“We all know that once sufferers are struggling, we will be able to by no means transfer rapid sufficient,” mentioned appearing NIH director Lawrence Tabak. “NIH is dedicated to a extremely coordinated and scientifically rigorous method to to find remedies that can supply reduction for the hundreds of thousands of other people residing with lengthy COVID.”

NIH will check the protection and effectiveness of the remedies – which come with each medicine and clinical units – in teams of 100 to 300 sufferers with lengthy Covid signs. 

The primary a part of the section two trial will check an extended dosing routine of Paxlovid to look if it improves lengthy Covid signs. 

Sufferers most often take Paxlovid inside 5 days of growing Covid signs to scale back their chance of hospitalization or loss of life, consistent with the Meals and Drug Management’s approval of the drug in Would possibly. To finish a complete process Paxlovid, sufferers should take 3 drugs two times an afternoon for 5 days. 

NIH mentioned some other a part of the learn about may also check for mind fog and memory-related signs.

The company will check clinical remedies like an internet mind coaching program referred to as BrainHQ and a tool that makes use of a small electrical present to stimulate mind process. 

NIH expects to release further scientific trials to check a minimum of seven extra remedies “within the coming months.”